Noticias

COLOMBIA PUEDE SER MÁS EFICIENTE EN CONTROL DE DENGUE, ZIKA Y CHIKUNGUNYA

  • Nivaldo Linares Pérez

Aunque Colombia tiene un fuerte sistema de atención; el Aedes, mosquito transmisor de los virus que transportan estas enfermedades, sigue siendo una amenaza latente que podría prevenirse de forma más efectiva si en el país se hiciera una inversión continua, estratificación de zonas de riesgo y trabajo colaborativo entre expertos......

Nota: Articulo publicado Clara Ocampo investigadora del CIDEIM y organizadora del Curso sobre la evaluación e impacto de las intervenciones contra enfermedades arbovirales (transmitidas por artrópodos) urbanas, especialmente el dengue, Zika y chikungunya, desarrollado y apoyado por el CIDEIM (Centro Internacional de Entrenamiento e Investigaciones Médicas), centro aliado de la Universidad ICESI con la colaboración de la Red DENTARGET y la participación de investigadores de Brasil, Colombia, Cuba, México y Estados Unidos.....

Diagnostic Doses of Insecticides for Adult Aedes aegypti to Assess Insecticide Resistance in Cuba

  • Nivaldo Linares Pérez

Autores: María Magdalena Rodríguez, Ariel Crespo, Daymi Hurtado, Ilario Fuentes, Jorge Rey and Juan Andrés Bisset

Abstract

The objective of this study was to determine diagnostic doses (DDs) of 5 insecticides for the Rockefeller susceptible strain of Aedes aegypti, using the Centers for Disease Control and Prevention (CDC) bottle bioassay as a tool for monitoring insecticide resistance in the Cuban vector control program. The 30-min DD values determined in this study were 13.5 μg/ml, 6.5 μg/ml, 6 μg/ml, 90.0 μg/ml, and 15.0 μg/ml for cypermethrin, deltamethrin, lambda-cyhalothrin, chlorpyrifos, and propoxur, respectively. To compare the reliability of CDC bottle bioassay with the World Health Organization susceptible test, 3 insecticide-resistant strains were evaluated for deltamethrin and lambda-cyhalothrin. Results showed that the bottles can be used effectively from 21 to 25 days after treatment and reused up to 4 times, depending on the storage time. The CDC bottle bioassay is an effective tool to assess insecticide resistance in field populations of Ae. aegypti in Cuba and can be incorporated into vector management programs using the diagnostic doses determined in this study.

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

  • Nivaldo Linares Pérez

Abstract

In response to the outbreak of Zika virus (ZIKV) infection in the Western Hemisphere and the recognition of a causal association with fetal malformations, the Global Virus Network (GVN) assembled an international taskforce of virologists to promote basic research, recommend public health measures and encourage the rapid development of vaccines, antiviral therapies and new diagnostic tests. In this article, taskforce members and other experts review what has been learned about ZIKV disease in humans, its modes of transmission and the cause and nature of associated congenital manifestations. After describing the make-up of the taskforce, we summarize the emergence of Zika in the Americas, Africa and Asia, its spread by mosquitoes, and current control measures. We then review the spectrum of primary Zika virus disease in adults and children, sites of persistent infection and sexual transmission, then examine what has been learned about maternal-fetal transmission and the congenital Zika syndrome, including knowledge obtained from studies in laboratory animals. Subsequent sections focus on vaccine development, antiviral therapeutics and new diagnostic tests. After reviewing current understanding of the mechanisms of emergence of Zika virus, we consider the likely future of the pandemic.

Disponible en Español en:

Antiviral Research